Iclip germany12/15/2023 ![]() The hands-on sessions in the laboratory will be complemented by presentations by established scientists that will share their experience on using iCLIP to answer different biological questions. We will further discuss the bioinformatics strategies for analysis of iCLIP data. We will guide the participants through the complete protocol, placing special emphasis on critical optimisation steps and controls. The major objective of this EMBO Practical Course is to disseminate the knowledge and proficiency in this technically challenging ribonomics method. Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) has established itself as a leading method to map the RNA interaction sites of a single RBP-of-interest with high resolution and in a quantitative manner. Understanding these interactions in a genome-wide manner is crucial for gaining a complete picture of an RBP’s specificity and function. In turn, RBPs can interact with hundreds to thousands of cellular RNAs by recognizing certain sequence motifs or structural elements. More information is available at EMBO Travel Grants.Throughout its life cycle, each RNA will interact dynamically with numerous RNA-binding proteins (RBPs) that determine how the RNA is processed, where it is localized, whether it is translated and finally how it is degraded. Selection of awardees is handled directly by the organizer who will notify all eligible participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form whether they wish to be considered for a travel grant. Travel GrantsĪ limited number of travel grants are available for participants. The maximum size should be 120 cm width/150 cm height. If you are interested in this option, please contact for more details. ![]() If positions remain open future rounds of selection will be performed, therefore you might be notified later.įor participants that already started with their own iCLIP experiments at home, it will be possible to bring their own samples under certain conditions. Selected participants will be contacted by e-mail by February 1st, 2017. Applications will be evaluated and selected by the organisers based on suitability for the course. Only complete applications will be considered.
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